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Nature MedicineArticle

Induced proximity comes of age

Nature Medicine · 09/03/2026

PubMed abstract / permitted excerpt

Nature Medicine, Published online: 03 September 2026; doi:10.1038/d41591-026-00045-z The first approved PROTAC for breast cancer validated the idea that medicines can work by bringing proteins together rather than by simply blocking them. Now, a new generation of proximity-based therapies is pushing that principle further.

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