Drakenterprises

Not clinical advice. Clinical Evidence is a current-awareness feed. It is not a clinical decision-support system, not medical advice, and not a substitute for clinical judgment, institutional protocols, or the original sources. Full text, NCCN recommendations, and Cochrane review bodies are not reproduced here.

Home · diabetes

Diabetes CareArticle

Comment on Ostrominski et al. Comparative Effectiveness of Tirzepatide Versus Dulaglutide or Semaglutide on Major Cardiovascular Events in Type 2 Diabetes and Cardiovascular Disease: Insights From Two Target-Trial Emulations.

Diabetes care · ADA · 08/20/2026

Authors: Zhang, Yazhou; Liu, Jianping

Publication types: Letter

PubMed abstract / permitted excerpt

We read with interest the report by Ostrominski et al. ( 1 ), which used two target-trial emulations to compare tirzepatide with dulaglutide or semaglutide among patients with type 2 diabetes and established atherosclerotic cardiovascular disease. The study is timely and carefully constructed. Our concern is not whether a statistical contrast was observed but what that contrast represents: superio

Full-text bodies are not stored. Official ADA RSS plus PubMed. Standards of Care via title/type filters, not scraped HTML.

Clinical Evidence