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TrialNCT06369259

Open-label Phase 2 Study of Avutometinib (RAF/MEK Clamp) in Combination With Defactinib (FAK Inhibitor) and Cetuximab in Patients With Unresectable, Anti-EGFR-Refractory Advanced Colorectal Cancer

Status
RECRUITING
Phase
PHASE2
Last update posted
09/04/2026
Start
02/24/2025
Sponsor
M.D. Anderson Cancer Center
Specialties
oncology

Conditions: Advanced Colorectal Cancer

Brief summary

To learn if avutometinib in combination with defactinib and cetuximab can help to control unresectable, anti-EGFR-refractory, advanced colorectal cancer.

Protocol documents and results are not hosted here. Verify every detail on ClinicalTrials.gov.

Clinical Evidence