Endothelial Dysfunction for Prognosis In Patients With preeClampSia
- Status
- RECRUITING
- Phase
- Not listed
- Last update posted
- 09/04/2026
- Start
- 05/08/2025
- Sponsor
- Heidelberg University
- Specialties
- emergency, cross-cutting
Conditions: Preeclampsia (PE); Hypertensive Disorder of Pregnancy
Brief summary
Preeclampsia is a pregnancy-specific hypertensive disorder and can progress rapidly to severe adverse outcomes affecting both the mother and the fetus. Endothelial and microcirculatory dysfunction mediate systemic preeclampsia-related organ dysfunctions. Changes in endothelial and vascular function in preeclampsia have been demonstrated through reduced flow-mediated vasodilation as a result of reduced availability of nitric oxide, which potentially persists up to several years postpartum. Hyperspectral imaging is a new innovative technology that allows to assess the peripheral microcirculation and perfusion non-invasively and contactless, but has never been evaluated in the context of preeclampsia before. This EPICS project (Endothelial dysfunction for Prognosis In patients with preeClampSia) is a prospective observational study and aims to investigate hyperspectral imaging as a new potential diagnostic and prognostic marker in preeclampsia.
Protocol documents and results are not hosted here. Verify every detail on ClinicalTrials.gov.
