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TrialNCT07405151

A Clinical Trial of Ifinatamab Deruxtecan in People With Advanced Esophageal Cancer (MK-3475-06F)

Status
RECRUITING
Phase
PHASE1, PHASE2
Last update posted
09/03/2026
Start
03/27/2026
Sponsor
Merck Sharp & Dohme LLC
Specialties
otolaryngology, oncology

Conditions: Oesophageal Squamous Cell Carcinoma

Brief summary

The purpose of this trial is to assess if ifinatamab deruxtecan (I-DXd) can treat esophageal squamous cell carcinoma (ESCC). I-DXd is an antibody-drug conjugate (ADC). An ADC attaches to a protein on cancer cells and delivers treatment to destroy those cells. The goal of this trial is to learn how many participants who receive I-DXd have the cancer respond, which means the cancer gets smaller or goes away.

Protocol documents and results are not hosted here. Verify every detail on ClinicalTrials.gov.

Clinical Evidence