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TrialNCT07804849

Oral Verapamil Among Newly Diagnosed Children and Adolescents With Type 1 Diabetes

Status
RECRUITING
Phase
PHASE2, PHASE3
Last update posted
09/04/2026
Start
08/20/2026
Sponsor
Ain Shams University
Specialties
cardiology, diabetes

Conditions: Type 1 Diabetes Mellitus

Brief summary

Type 1 diabetes (T1D) in children involves autoimmune destruction of pancreatic ß- cells, leading to insulin deficiency. Verapamil is an L-type calcium channel blocker that has been used for decades to treat hypertension and certain cardiac conditions. Recent research has revealed its potential as a ß- cell-protective agent. Hence this study will evaluate the effect of once-daily oral verapamil on pancreatic ß- cell reserve , glycemic metrics and daily insulin requirements in children and adolescents with T1D.

Protocol documents and results are not hosted here. Verify every detail on ClinicalTrials.gov.

Clinical Evidence